Viral suppressors from members of the family Closteroviridae combating antiviral RNA silencing: a tale of a sophisticated arms race in host-pathogen interactions

Phytopathology Research

Muhammad Tariqjaveed¹  Tahir Farooq²  Sijia Liu³  Tao Zhou³  Xi Chen³  Tong Jiang³  Muhammad Dilshad Hussain³ 

[1] Department of Plant Pathology, and Ministry of Agriculture and Rural Affairs Key Laboratory of Pest Monitoring and Green Management, and Ministry of Education Joint Laboratory for International Cooperation in Crop Molecular Breeding, China Agricultural University;Plant Protection Research Institute and Guangdong Provincial Key Laboratory of High Technology for Plant Protection, Guangdong Academy of Agricultural Sciences;State Key Laboratory for Agro-Biotechnology, and Ministry of Agriculture and Rural Affairs, Key Laboratory for Pest Monitoring and Green Management, Department of Plant Pathology, China Agricultural University;

关键词: Closterovirids;    Antiviral RNA silencing;    Viral pathogenicity;    Plant immunity;    Crop disease;   

DOI  :  10.1186/s42483-021-00104-y

来源: DOAJ

【 摘 要 】

Abstract RNA silencing is an evolutionarily homology-based gene inactivation mechanism and plays critical roles in plant immune responses to acute or chronic virus infections, which often pose serious threats to agricultural productions. Plant antiviral immunity is triggered by virus-derived small interfering RNAs (vsiRNAs) and functions to suppress virus further replication via a sequence-specific degradation manner. Through plant-virus arms races, many viruses have evolved specific protein(s), known as viral suppressors of RNA silencing (VSRs), to combat plant antiviral responses. Numerous reports have shown that VSRs can efficiently curb plant antiviral defense response via interaction with specific component(s) involved in the plant RNA silencing machinery. Members in the family Closteroviridae (closterovirids) are also known to encode VSRs to ensure their infections in plants. In this review, we will focus on the plant antiviral RNA silencing strategies, and the most recent developments on the multifunctional VSRs encoded by closterovirids. Additionally, we will highlight the molecular characters of phylogenetically-associated closterovirids, the interactions of these viruses with their host plants and transmission vectors, and epidemiology.

【 授权许可】

Unknown