Egyptian practical guidance in hypertriglyceridemia management 2021

The Egyptian Heart Journal

Nabil Farag¹  Magdy El Sharkawy¹  Mina Samy²  Fouad Fawzy²  Hesham Salah El Din Taha²  Mohamed Aboul²  Mostafa Abdrabou²  Hossam Mahrous²  Hossam Kandil²  Juliette Bahgat²  Mirna Mamdouh Shaker²  Abbas Oraby³ 

[1] Ain-Shams University;Department of Cardiology, Faculty of Medicine, Cairo University;Suez Canal University;

关键词: Hypertriglyceridemia;    Dyslipidemia;    Practical guidance;    Atherosclerotic cardiovascular disease;   

DOI  :  10.1186/s43044-021-00235-9

来源: DOAJ

【 摘 要 】

Abstract Hypertriglyceridemia (HTG) is a very common, yet underappreciated problem in clinical practice. Elevated triglyceride (TG) levels are independently associated with atherosclerotic cardiovascular disease (ASCVD) risk. Furthermore, severe HTG may lead to acute pancreatitis. Although LDL-guided statin therapy has improved ASCVD outcomes, residual risk remains. Recent trials have demonstrated that management of high TG levels, in patients already on statin therapy, reduces the rate of major vascular events. Few guidelines were issued, providing important recommendations for HTG management strategies. The goal of treatment is to reduce the risk of ASCVD and acute pancreatitis. The management stands on lifestyle modification, detection of secondary causes of HTG and pharmacological therapy, when indicated. In this guidance we review the causes and classification of HTG and summarize the current methods for risk estimation, diagnosis and treatment. The present guidance provides a focused update on the management of HTG, outlined in a simple user-friendly format, with an emphasis on the latest available data.

【 授权许可】

Unknown