Childhood Inflammatory Bowel Disease in Libya: Epidemiological and Clinical Features

Libyan Journal of Medicine

关键词: Inflammatory bowel disease;    Ulcerative colitis;    Crohn’s disease;    Indeterminate colitis;    Juvenile onset inflammatory bowel disease.;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background & Aims: Inflammatory bowel disease is thought to be rare in Libya. The aim is todetermine the prevalence of juvenile onset inflammatory bowel disease in Libya. Setting: Al-Fatehchildrens’ hospital, Benghazi, Libya. Methods: This is a retrospective study of all cases diagnosedover 10 years (1997-2006) with either ulcerative colitis, Crohn’s disease or indeterminate colitis.Inclusion criteria were age <15 years at time of presentation who were resident in the eastern part ofthe country and who diagnosed with inflammatory bowel disease. Clinical features were outlinedusing a proforma. Results: Sixteen cases were diagnosed with inflammatory bowel disease, ofwhom 11 were males (M:F ratio of 1.5:1). The prevalence and incidence rates in the year 2006 were3.6 and 0.9 per 100,000 children, respectively. The incidence rate increased from 0.2 in 2002 to 0.9 in2006 (Z score of 39.87, p= 0.00). The age at presentation ranged from 5 months to 14 years. Ninehad Crohn’s disease (6 males) and 6 had ulcerative colitis (4 males). One patient had indeterminatecolitis. The most common clinical features were diarrhea in 10 (62.5%), abdominal pain, anorexia andweight loss in 9 (56.2%), anemia in 7 (43.75%) and vomiting in 6 (37%). Ileopancolitis was found in 3patients whereas 6 patients had ileocecal disease. Conclusions: Childhood inflammatory boweldisease in this population is not so rare and it is increasing. The clinical pattern is similar to thatreported by others.

【 授权许可】

Unknown