Nano‐Biomedicine based on Liquid Metal Particles and Allied Materials

Advanced NanoBiomed Research

Xuyang Sun¹  Jing Liu¹  Minghui Duan²  Hongzhang Wang²  Bo Yuan²  Linlin Fan²  Rui Guo²  Xuelin Wang³ 

[1] Beijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P.R. China;Department of Biomedical Engineering School of Medicine Tsinghua University Beijing 100084 P.R. China;School of Medical Science and Engineering Beihang University Beijing 100191 P.R. China;

关键词: biomaterials;    liquid metals;    nano-biomedicine;    nanoparticles;    synthesis methods;   

DOI  :  10.1002/anbr.202000086

来源: DOAJ

【 摘 要 】

Liquid metals (LMs) have emerged as a new class of functional materials with attractive characteristics of low melting points and metal properties. Remarkable features, such as biocompatibility, injectability, plasticity, conductivity, and shape transformability, have rendered them as excellent candidates to tackle challenging biomedical issues, such as tumor clinics, tissue engineering, and even nerve connection. Scaling down the droplet size offers more opportunities in surface engineering and functionalization, thus providing broad biomedical scenarios expanding from drug delivery, enhanced bioheat transfer, tumor therapeutics, and bioelectronics to nanorobots. Despite in its infancy stage, a summary about the advancement of LM biomedical nanomaterials is urgently needed. This review aims to highlight the advantages of gallium‐based LM nanoparticles enabled nano‐biomedicine, to summarize the recent synthesis methods with diverse LM compositions, structures and surface modifications, and to introduce their typical state‐of‐the‐art biomedical applications. Challenges and opportunities are also discussed in the end.

【 授权许可】

Unknown