TREATMENT IN PATIENTS WITH MUSCLE NONINVASIVE CARCINOMA OF THE URINARY BLADDER AFTER UNSUCCESSFUL INTRAVESICULAR BCG THERAPY

Onkourologiâ

K. M. Figurin¹ 

[1] N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow;

关键词: muscle noninvasive carcinoma of the urinary bladder;    BCG;    BCG therapy failures;    progression;    cystectomy;    chemotherapy;   

DOI  :  

来源: DOAJ

【 摘 要 】

Failures of BCG therapy for muscle noninvasive carcinoma of the urinary bladder are classified as BCG refractoriness, BCG resistance, postBCG-therapy recurrences. Some patients are observed to be BCG intolerant, which makes the therapy discontinued. Detectable BCG refractoriness and early recurrences are associated with a high risk of progression and high tumor-specific mortality and are indications for emergency cystectomy. Preference should be given to early cystectomy if high risk group patients have additional poor prognostic factors for disease progression. In patients with BCG therapy failures, medical treatment should be performed only within research programs.

【 授权许可】

Unknown