Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects

Frontiers in Bioengineering and Biotechnology

Yunfeng Lin¹  Yu Xie²  Zhiqiang Liu²  Xingyu Chen² 

[1] College of Biomedical Engineering, Sichuan University, Chengdu, China;State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China;

关键词: tetrahedral framework nucleic acid;    tFNA;    neurological disorders;    DNA nanomaterials;    tetrahedral DNA nanomaterials;   

DOI  :  10.3389/fbioe.2021.782237

来源: DOAJ

【 摘 要 】

Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, is widely applied in diverse biomedical fields. Due to its high programmability, biocompatibility, tissue permeability as well as its capacity for cell proliferation and differentiation, tFNA presents a powerful tool that could overcome potential barriers in the treatment of neurological disorders. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.

【 授权许可】

Unknown