Genomics enters the deep learning era

PeerJ

Etienne Routhier¹  Julien Mozziconacci² 

[1] LPTMC, Sorbonne Université, Paris, France;StrInG Lab, Museum National d’Histoire Naturelle, Paris, France;

关键词: Deep learning;    Genomics;    Genetics;    Epigenomics;    Bioinformatics;    Review;   

DOI  :  10.7717/peerj.13613

来源: DOAJ

【 摘 要 】

The tremendous amount of biological sequence data available, combined with the recent methodological breakthrough in deep learning in domains such as computer vision or natural language processing, is leading today to the transformation of bioinformatics through the emergence of deep genomics, the application of deep learning to genomic sequences. We review here the new applications that the use of deep learning enables in the field, focusing on three aspects: the functional annotation of genomes, the sequence determinants of the genome functions and the possibility to write synthetic genomic sequences.

【 授权许可】

Unknown