Applied Sciences | |
Poly(α-hydroxy Acids)-Based Cell Microcarriers | |
Jose-Ramon Sarasua1  Aitor Larrañaga2  | |
[1] POLYMAT, Faculty of Engineering, University of the Basque Country (UPV/EHU), Bilbao 480130, Spain;;Department of Mining-Metallurgy Engineering and Materials Science & | |
关键词: polylactide; poly(α-hydroxyacids); cell microcarriers; microparticles; tissue engineering; | |
DOI : 10.3390/app6120436 | |
来源: DOAJ |
【 摘 要 】
Biodegradable poly(α-hydroxyacids) have gained increasing interest in the biomedical field for their use as cell microcarriers thanks to their biodegradability, biocompatibility, tunable mechanical properties/degradation rates and processability. The synthesis of these poly(α-hydroxyacids) can be finely controlled to yield (co)polymers of desired mechanical properties and degradation rates. On the other hand, by simple emulsion-solvent evaporation techniques, microspheres of controlled size and size distribution can be fabricated. The resulting microspheres can be further surface-modified to enhance cell adhesion and proliferation. As a result of this process, biodegradable microcarriers with advanced functionalities and surface properties that can be directly employed as injectable cell microcarriers are obtained.
【 授权许可】
Unknown