Plaque Erosion: A Distinctive Pathological Mechanism of Acute Coronary Syndrome

Frontiers in Cardiovascular Medicine

Shaoyu Liu¹  Ying Lv³  Jinyu Qi³  Haibo Jia³  Xiaoyi Bao³  Xing Luo³  Xiaoxuan Bai³  Bo Yu³  Xiuzhu Weng³ 

[1] Bin Xian People's Hospital, Harbin, China;Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China;Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, China;

关键词: acute coronary syndrome;    plaque erosion;    plaque rupture;    optical coherence tomography;    biomarker 2;   

DOI  :  10.3389/fcvm.2021.711453

来源: DOAJ

【 摘 要 】

Plaque erosion (PE) is one of the most important pathological mechanisms underlying acute coronary syndrome (ACS). The incidence of PE is being increasingly recognized owing to the development and popularization of intracavitary imaging. Unlike traditional vulnerable plaques, eroded plaques have unique pathological characteristics. Moreover, recent studies have revealed that there are differences in the physiopathological mechanisms, biomarkers, and clinical outcomes between PE and plaque rupture (PR). Accurate diagnosis and treatment of eroded plaques require an understanding of the pathogenesis of PE. In this review, we summarize recent scientific discoveries of the pathological characteristics, mechanisms, biomarkers, clinical strategies, and prognosis in patients with PE.

【 授权许可】

Unknown