The crosstalk between the cardiovascular and the immune system

Vascular Biology

Francesco Tona¹  Carlo Dal Lin¹  Elena Osto² 

[1] Department of Cardiac, Thoracic and Vascular Sciences, Padua University-Hospital, Padua, Italy;University and University Hospital Zurich, Institute of Clinical Chemistry, Zurich, Switzerland;

关键词: endothelial dysfunction;    inflammation;    stress;    immune disease;    cardiovascular disease;   

DOI  :  https://doi.org/10.1530/VB-19-0023

来源: DOAJ

【 摘 要 】

The heart and the immune system are highly integrated systems cross-talking through cytokines, hormones and neurotransmitters. Their balance can be altered by numerous physical or psychological stressors leading to the onset of inflammation, endothelial dysfunction and tissue damage. Here, we review the main players and mechanisms involved in the field. A new research paradigm, which considers also novel contributors, like endothelial cells, is needed to better understand the pathophysiology of immune-mediated cardiovascular disorders and beyond.

【 授权许可】

Unknown