Global Perspectives on Immunization Against SARS-CoV-2 During Pregnancy and Priorities for Future Research: An International Consensus Paper From the World Association of Infectious Diseases and Immunological Disorders

Frontiers in Immunology

Nasamon Wanlapakorn¹  Eline Tommelein²  Susanna Esposito⁵  Katie L. Flanagan⁶  Petra Zimmermann⁸  Miguel O’Ryan⁹  Marco A. Safadi^1,10  Vassiliki Papaevangelou^1,11  Kirsten Maertens^1,12  Vicens Diaz-Brito^1,13  Shabir A. Madhi^1,14  Saad B. Omer^1,15  Michelle L. Giles^1,16  Bahaa Abu-Raya^1,19  Gayatri Amirthalingam^2,20 

[1] Infectious Diseases Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium;0Department of Infectious Diseases, Parc Sanitari Sant Joan de Déu,, Barcelona, Spain;0School of Health and Biomedical Science, Royal Melbourne Institute of Technology (RMIT) University, Melbourne, VIC, Australia;1Department of Immunology and Pathology, Monash University, Melbourne, VIC, Australia;1Department of Pharmacy, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium;2Tasmanian Vaccine Trial Centre, Clifford Craig Foundation, Launceston General Hospital, Launceston, TAS, Australia;3Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland;4Department of Paediatrics, Fribourg Hospital HFR, Fribourg, Switzerland;5Microbiology and Mycology Program, Institute of Biomedical Sciences and Millennium Institute of Immunology and Immunotherapy, Faculty of Medicine, University of Chile, Santiago de Chile, Chile;6Department of Pediatrics, Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil;7National and Kapodistrian University of Athens, Third Department of Pediatrics, University Hospital Attikon, Athens, Greece;;8Centre for the Evaluation of Vaccination, Vaccine &9Center of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;African Leadership in Vaccinology Expertise, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States;Department of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia;Department of Internal Medicine (Infectious Diseases), Yale School of Medicine, New Haven, CT, United States;Department of Obstetrics and Gynaecology, Monash University, Melbourne, VIC, Australia;Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada;Immunisation and Countermeasures Division, National Infection Service, Public Health England, London, United Kingdom;School of Medicine, Faculty of Health Sciences, University of Tasmania, Launceston, TAS, Australia;South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;

关键词: maternal immunization;    pregnant women;    SARS-CoV-2;    COVID-19;    maternal vaccination program;   

DOI  :  10.3389/fimmu.2021.808064

来源: DOAJ

【 摘 要 】

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with a higher risk for severe morbidity and mortality when compared with infection in non-pregnant women of childbearing age. An increasing number of countries recommend immunization against SARS-CoV-2 in pregnant women. Recent studies provide preliminary and supportive evidence on safety, immunogenicity and effectiveness of coronavirus disease 2019 (COVID-19) vaccines in pregnant women; however, important knowledge gaps remain which warrant further studies. This collaborative consensus paper provides a review of the current literature on COVID-19 vaccines in pregnant women, identifies knowledge gaps and outlines priorities for future research to optimize protection against SARS-CoV-2 in the pregnant women and their infants.

【 授权许可】

Unknown