Learning Yeast Genetics from Miro Radman

Cells

JamesE. Haber¹ 

[1] Department of Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA;

关键词: Saccharomyces cerevisiae;    budding yeast;    mismatch repair;    DNA damage response;    SOS;    homologous recombination;   

DOI  :  10.3390/cells10040945

来源: DOAJ

【 摘 要 】

Miroslav Radman’s far-sighted ideas have penetrated many aspects of our study of the repair of broken eukaryotic chromosomes. For over 35 years my lab has studied different aspects of the repair of chromosomal breaks in the budding yeast, Saccharomyces cerevisiae. From the start, we have made what we thought were novel observations that turned out to have been predicted by Miro’s extraordinary work in the bacterium Escherichia coli and then later in the radiation-resistant Dienococcus radiodurans. In some cases, we have been able to extend some of his ideas a bit further.

【 授权许可】

Unknown