Polyphenols and Brazilian red propolis incorporated into a total-etching adhesive system help in maintaining bonding durability

Heliyon

Iverson Iago Soares Ferreira¹  Arthur Bezerra de Barros Rocha²  Johnnatan Duarte de Freitas³  Ticiano Gomes do Nascimento³  Eryck Canabarra Ávila⁴  Teresa de Lisieux Guedes Ferreira Lôbo⁴  Bruna Muritiba de Barros⁴  Matheus Corrêa da Silva⁴  Isabel Cristina Celerino de Moraes Porto⁴  José Marcos dos Santos Oliveira⁴  Marcos Paulo Santana de Oliveira⁴  Jeniffer Mclaine Duarte de Freitas⁵ 

[1] Corresponding author.;Laboratory of Pharmaceutical and Food Analysis, Postgraduate Program in Pharmaceutical Sciences, Institute of Pharmaceutical Sciences, Federal University of Alagoas, Campus A. C. Simões, CEP 57072-970, Maceió, Alagoas, Brazil;Laboratory of Pharmaceutical and Food Analysis, Postgraduate Program in Pharmaceutical Sciences, Institute of Pharmaceutical Sciences, Federal University of Alagoas, Campus A. C. Simões, CEP 57072-970, Maceió, Alagoas, Brazil;Laboratoty of Characterization and Analysis of Biomaterials, Faculty of Dentistry, Federal University of Alagoas, Campus AC Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, CEP 57072-970, Maceió, Alagoas, Brazil;Postgraduate Program in Health Research, Cesmac University Center, Rua Prof. Ângelo Neto, 51, Farol, CEP 57051-530, Maceió, Alagoas, Brazil;

关键词: Dentin bonding agents;    Propolis;    Quercetin;    Resveratrol;    Tensile strength;    Degree of conversion;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objectives: The aim of this study was to evaluate the degree of conversion and bond strength of a commercial dental adhesive modified by the incorporation of quercetin, resveratrol (RES), and Brazilian red propolis (BRP). Methods: BRP markers were identified using ultra-performance liquid chromatography coupled with a diode array detector, and the antioxidant activity (AAO) of the three substances was analyzed. Single Bond 2 adhesive (3M ESPE) was modified by adding BRP, quercetin, and RES, separately, at 20 μg/mL, 250 μg/mL, and 500 μg/mL, respectively. The degree of conversion (DC) was measured using near-infrared spectroscopy 24 h after photopolymerization. Measurements of the resin-dentin microtensile bond strength (μTBS) were carried out after 1 day and 1 year. Student's t test and ANOVA with Tukey's test were used for data analysis (α = 0.05). Results: The markers daidzein, liquiritigenin, pinobanksin, isoliquiritigenin, formononetin, pinocembrin, and biochanin A were found in the ethanolic extract of BRP. Quercetin, RES, and BRP showed high AAO. The DC of the tested adhesives remained adequate for this category of material, with a slight increase in the DC of adhesives with quercetin and BRP (P > 0.05). Comparisons between μTBS measurements made at 1 day and 1 year showed that, contrary to the control group, μTBS values for all modified adhesives were maintained after 1 year in distilled water (P > 0.05). Conclusions: These findings suggest that quercetin, RES, or BRP might be useful in adhesive dentistry to help improve hybrid layer resistance. Clinical significance: Dentin bonding agents with quercetin, RES, and BRP have potential to increase the longevity of composite restorations.

【 授权许可】

Unknown