Acute phase response of sole ulcer, white line disease and digital dermatitis in dairy cows

Veterinary and Animal Science

Isto Talvio¹  Hertta Pirkkalainen²  Toomas Orro²  Timo Soveri²  Minna Kujala-Wirth³ 

[1] Corresponding author.;Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Paroninkuja 20, Saarentaus, 04920 Finland;Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Science, Kreutzwaldi 62, Tartu, 51006 Estonia;

关键词: Acute phase protein;    Acute phase response;    Dairy cow;    Digital dermatitis;    Sole ulcer;    White line disease;   

DOI  :  

来源: DOAJ

【 摘 要 】

Hoof disorders cause lameness and welfare problems for dairy cattle. Acute phase proteins, including serum amyloid A and haptoglobin, with increased rectal temperature and interleukin-6 concentrations, are markers of acute phase response. This study assessed the inflammatory response of cows with either sole ulcer, white line disease or digital dermatitis compared to healthy cows. Another aim was to monitor the inflammatory response changes over time after diagnosis (at hoof trimming, seven and 14 days later) in cows with different hoof disorders.Serum amyloid A concentration in cows with sole ulcer was significantly higher compared with the control group (cows with no hoof lesions) within the two-week study period. Interleukin-6 and rectal temperature declined from day zero to day seven in the sole ulcer group. These results suggest that sole ulcers initiate a long lasting systemic inflammatory response in dairy cows.

【 授权许可】

Unknown