Tobacco smoking dependence in patients with depressive spectrum mental disorders: clinical, pathogenetic, and therapeutic aspects

Nevrologiâ, Nejropsihiatriâ, Psihosomatika

Z. I. Storozheva¹  O. I. Speranskaya¹  S. A. Trushchelev¹ 

[1] V.P. Serbsky National Medical Research Centre for Psychiatry and Narcology, Ministryof Health;

关键词: depression;    tobacco smoking;    pathogenesis;    genetics;    comorbidity;    treatment;   

DOI  :  10.14412/2074-2711-2019-2-115-120

来源: DOAJ

【 摘 要 】

This review considers the clinical and pathogenetic aspects of an association between tobacco smoking dependence and depressive spectrum disorders. The comorbidity of these disorders has been established to be to a large extent determined by their common genetic bases. This association substantially affects the efficiency of treatment. Resistance to anti-nicotine and antidepressant medications is associated precisely with the comorbidity of these diseases. To enhance the efficiency of treatment, it is promising to include non-drug methods into the therapeutic complex. This makes it possible to achieve a gradual reduction in tobacco withdrawal syndrome and to prevent an exacerbation of comorbid depression.

【 授权许可】

Unknown