Do Centenarians Die Healthier than Younger Elders? A Comparative Epidemiological Study in Spain

Journal of Clinical Medicine

Ignatios Ioakeim-Skoufa¹  Mónica Machón Antonio Gimeno-Miguel¹  Mercedes Aza-Pascual-Salcedo²  Mercedes Clerencia-Sierra²  Alexandra Prados-Torres²  Beatriz Poblador-Plou³  Francisca González-Rubio⁴ 

[1] EpiChron Research Group, 50009 Zaragoza, Spain;Aragon Health Service (SALUD);EpiChron Research Group, IIS Aragón, 50009 Zaragoza, Spain;Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), 28222 Madrid, Spain;

关键词: aged 80 and over;    delivery of healthcare;    electronic health records;    multimorbidity;    multiple chronic conditions;    polypharmacy;   

DOI  :  10.3390/jcm9051563

来源: DOAJ

【 摘 要 】

This study aims to describe the clinical course, drug use, and health services use characteristics during the last year of life of elders who die being centenarians and to identify key aspects differentiating them from elders who die at an earlier age, with a particular focus on sex differences. We conducted an observational, population-based study in the EpiChron Cohort (Aragón, Spain). The population was stratified by sex and into three age sub-populations (80–89, 90–99, and ≥100 years), and their characteristics were described and compared. Multimorbidity was the rule in our elders, affecting up to 3 in 4 centenarians and 9 in 10 octogenarians and nonagenarians. Polypharmacy was also observed in half of the centenarian population and in most of the younger elders. Risk factors for cardiovascular disease (i.e., hypertension, dyslipidaemia, diabetes), cerebrovascular disease and dementia were amongst the most common chronic conditions in all age groups, whereas the gastroprotective drugs and antithrombotic agents were the most dispensed drugs. Centenarians presented in general lower morbidity and treatment burden and lower use of both primary and hospital healthcare services than octogenarians and nonagenarians, suggesting a better health status. Sex-differences in their clinical characteristics were more striking in octogenarians and tended to decrease with age.

【 授权许可】

Unknown