Cross-Neutralization between Human and African Bat Mumps Viruses

Emerging Infectious Diseases

关键词: bat virus;    Chimeric virus;    mumps virus;    African bat mumps virus;    neutralization;    viruses;   

DOI  :  10.3201/eid2204.151116

来源: DOAJ

【 摘 要 】

Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.

【 授权许可】

Unknown