From “Dark Matter” to “Star”: Insight Into the Regulation Mechanisms of Plant Functional Long Non-Coding RNAs

Frontiers in Plant Science

Yaoqi Zhou³  Ru Yu⁴  Qingshuai Chen⁴  Pingping Huang⁴  Kui Liu⁴  Zanxia Cao⁴  Jihua Wang⁴  Bailing Zhou⁴ 

[1] Institute for Glycomics and School of Information and Communication Technology, Griffith University, Gold Coast, QLD, Australia;Institute for Systems and Physical Biology, Shenzhen Bay Laboratory, Shenzhen, China;Peking University Shenzhen Graduate School, Shenzhen, China;Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou, China;

关键词: plants;    long non-coding RNAs;    interaction;    functional molecular;    gene expression;   

DOI  :  10.3389/fpls.2021.650926

来源: DOAJ

【 摘 要 】

Long non-coding RNAs (lncRNAs) play a vital role in a variety of biological functions in plant growth and development. In this study, we provided an overview of the molecular mechanisms of lncRNAs in interacting with other biomolecules with an emphasis on those lncRNAs validated only by low-throughput experiments. LncRNAs function through playing multiple roles, including sponger for sequestering RNA or DNA, guider or decoy for recruiting or hijacking transcription factors or peptides, and scaffold for binding with chromatin modification complexes, as well as precursor of microRNAs or small interfering RNAs. These regulatory roles have been validated in several plant species with a comprehensive list of 73 lncRNA–molecule interaction pairs in 16 plant species found so far, suggesting their commonality in the plant kingdom. Such initial findings of a small number of functional plant lncRNAs represent the beginning of what is to come as lncRNAs with unknown functions were found in orders of magnitude more than proteins.

【 授权许可】

Unknown