Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis

Frontiers in Nutrition

Lei Xu¹  Yanan Liu¹  Xin Zhang¹  Zufang Wu¹  Chi-Tang Ho² 

[1] Department of Food Science and Engineering, Ningbo University, Ningbo, China;Department of Food Science, Rutgers University, New Brunswick, NJ, United States;

关键词: tea polyphenols;    COVID-19;    gut microbiota;    gut-lung axis;    antiviral;   

DOI  :  10.3389/fnut.2022.899842

来源: DOAJ

【 摘 要 】

Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.

【 授权许可】

Unknown