期刊论文详细信息
Arabian Journal of Chemistry
Synthesis, characterization and self-assembly of novel fluorescent alkoxy-substituted 1, 4-diarylated 1, 2, 3-triazoles organogelators
Aisha Hossan1  Salhah D. Al-Qahtani2  Rua B. Alnoman3  Amerah Alsoliemy4  Razan M. Snari4  Abrar Bayazeed4  Nashwa M. El-Metwaly4 
[1] Chemistry Department, Faculty of science, King Khalid University, Abha, Saudi Arabia;Department of Chemistry ,College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia;Department of Chemistry, College of Science, Taibah University, Madinah, P.O. Box 344, Saudi Arabia;Department of Chemistry, Faculty of Applied Science, Umm-Al-Qura University, Makkah 24230, Saudi Arabia;
关键词: CuAAC;    1;    2;    3-Triazole;    Fluorescence;    Self-assembly;    Nanofibers;   
DOI  :  
来源: DOAJ
【 摘 要 】

Novel organogelators based on fluorescent alkoxy-substituted 1,4-diarylated 1, 2, 3-triazoles are reported. The findings monitored in the current study promoted the development of inventive compacted supramolecular architectures generated by self-assembly of the prepared triazole-based organogelators. The synthesis, characterization and gelation properties of the current novel alkoxy-substituted 1,4-diarylated 1, 2, 3-triazole arms were described. The synthesis procedures were accomplished by using Cu-catalyzed azide-alkyne cycloaddition (CuAAC) of alkoxy-substituted aryl azide with aryl bearing terminal alkyne subtituents and alkoxy chains of different lengths. The alkoxy-substituted of 1, 4-diarylated 1, 2, 3-triazole derivatives bearing different alkoxy chains were characterized by FTIR, 1H/13C NMR, and elemental analysis. The 1, 4-diarylated 1, 2, 3-triazoles with longer alkoxy terminal groups demonstrated improved gelation properties compared to those with shorter alkoxy terminals. The morphologies of the self-assembled alkoxy-substituted 1, 4-diarylated 1, 2, 3-triazoles were investigated using scanning electron microscopy (SEM), which demonstrated arrangements of highly ordered nanofibers, forced by π-stacks and van der Waals interactions. The antibacterial activity and cytotoxicity of the newly synthesized triazoles was investigated to verify the potential use of the present triazole gelators for a variety of applications, such as drug delivery.

【 授权许可】

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