Treatment Progress for EGFR Wild-type Advanced Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer

Feng MA¹  Jing ZHANG¹  Lixia ZHAO¹  Junfeng ZHAO¹  Wei MENG¹  Xiaohua HE¹  Xiaoyu SHI¹ 

[1] Department of Medical Oncology, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China;

关键词: Lung neoplasms;    Epidermal growth factor receptor;    Wild type;    Chemotherapy;    Targeted therapy;    Maintenance treatment;   

DOI  :  10.3779/j.issn.1009-3419.2014.07.14

来源: DOAJ

【 摘 要 】

Lung cancer is the leading cause of death from cancer in the world. The treatment remains one of the most challenging tasks in the medical world. The discovery and development of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) have had a major impact in the treatment of non small cell lung cancer (NSCLC). But the efficacy of EGFR-TKI in EGFR wild-type patients is limited, and the limited EGFR mutation incidence also prompts researchers to study what is the best treatment choice for patients with NSCLC who are negative for EGFR mutations. This review will discuss the research status in treatment choice for EGFR wild-type NSCLC.

【 授权许可】

Unknown