期刊论文详细信息
Crystals | |
Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers | |
Suraj Pandey1  Ishwor Poudyal1  TekNarsingh Malla1  | |
[1] Physics Department, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA; | |
关键词: time-resolved crystallography; pump-probe serial femtosecond crystallography; X-ray free electron lasers; diffraction before destruction; difference electron density map; power titration; | |
DOI : 10.3390/cryst10070628 | |
来源: DOAJ |
【 摘 要 】
With time-resolved crystallography (TRX), it is possible to follow the reaction dynamics in biological macromolecules by investigating the structure of transient states along the reaction coordinate. X-ray free electron lasers (XFELs) have enabled TRX experiments on previously uncharted femtosecond timescales. Here, we review the recent developments, opportunities, and challenges of pump-probe TRX at XFELs.
【 授权许可】
Unknown