Gold-catalyzed oxycyclization of allenic carbamates: expeditious synthesis of 1,3-oxazin-2-ones

Beilstein Journal of Organic Chemistry

Israel Fernández¹  Benito Alcaide²  M. Teresa Quirós²  Pedro Almendros³ 

[1] Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense de Madrid, 28040-Madrid, Spain;Grupo de Lactamas y Heterociclos Bioactivos, Departamento de Química Orgánica I, Unidad Asociada al CSIC, Facultad de Química, Universidad Complutense de Madrid, 28040-Madrid, Spain;Instituto de Química Orgánica General (IQOG), Consejo Superior de Investigaciones Científicas (CSIC), Juan de la Cierva 3, 28006-Madrid, Spain;

关键词: allenes;    computational chemistry;    gold;    gold catalysis;    heterocycles;    reaction mechanisms;   

DOI  :  10.3762/bjoc.9.93

来源: DOAJ

【 摘 要 】

A combined experimental and computational study on regioselective gold-catalyzed synthetic routes to 1,3-oxazinan-2-ones (kinetically controlled products) and 1,3-oxazin-2-one derivatives (thermodynamically favored) from easily accessible allenic carbamates has been carried out.

【 授权许可】

Unknown