期刊论文详细信息
| Genetics and Molecular Biology | |
| Detection of determinant genes and diagnostic via Item Response Theory | |
| 关键词: Item Response Theory (IRT); predisposition; propensity; logistic model; | |
| DOI : 10.1590/S1415-47572004000400033 | |
| 来源: DOAJ | |
【 摘 要 】
This work presents a method to analyze characteristics of a set of genes that can have an influence in a certain anomaly, such as a particular type of cancer. A measure is proposed with the objective of diagnosing individuals regarding the anomaly under study and some characteristics of the genes are analyzed. Maximum likelihood equations for general and particular cases are presented.
【 授权许可】
Unknown
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