Detection of determinant genes and diagnostic via Item Response Theory

Genetics and Molecular Biology

Héliton Ribeiro Tavares²  Dalton Francisco De Andrade¹  Carlos Alberto De Bragança Pereira¹ 

[1] ,Universidade Federal do Pará Departamento de Estatística Belém PA ,Brazil

关键词: Item Response Theory (IRT);    predisposition;    propensity;    logistic model;   

DOI  :  10.1590/S1415-47572004000400033

来源: SciELO

【 摘 要 】

This work presents a method to analyze characteristics of a set of genes that can have an influence in a certain anomaly, such as a particular type of cancer. A measure is proposed with the objective of diagnosing individuals regarding the anomaly under study and some characteristics of the genes are analyzed. Maximum likelihood equations for general and particular cases are presented.

【 授权许可】

CC BY   
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