In vitro antibacterial activity and phytochemical analysis of hexane extract of Vicia sativa

Bangladesh Journal of Pharmacology

Bilal Ahmed¹  Mahrukh Karim¹  Mohammad Saleem¹  Maria Rafiq¹  Bashir Ahmad²  Muhammad Imran Qadir³ 

[1] College of Pharmacy, GC University Faisalabad;Department of Pharmacy, University of Lahore;Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan;

关键词: Antibacterial;    HPLC;    Phytochemical analysis;    Vicia sativa;   

DOI  :  

来源: DOAJ

【 摘 要 】

Vicia sativa is traditionally used medicinal plant in skin infections, asthma, bronchitis, urinary diseases and also used as antiseptic, anti-poison, aphrodisiac, anti rheumatic and antipyretic. In the present study n-hexane extract of V. sativa was evaluated for the antibacterial activity against pathogenic bacteria Staphylococcus aureus, Bacillus atrophaeus, Escherichia coli and S. epidermidis by disc diffusion method. Minimum inhibitory concentration of the n-hexane extract against all bacteria was determined by broth dilution method. Preliminary phytochemical analysis and HPLC analysis showed the presence of a number of bioactive constituents which exhibits antibacterial activity. So the current study showed that V. sativa possesses the significant antibacterial activity.

【 授权许可】

Unknown