Integration of Microresonant Sensor into a Microfluidic Platform for the Real Time Analysis of Platelets-Collagen Interaction in Flow Condition

Proceedings

Wilfrid Boireau¹  Benoît Le Roy de Boiseaumarié¹  Thérèse Leblois¹  Aleksandr Oseev¹  Alain Rouleau¹  Franck Chollet¹  Jean-François Manceau¹  Fabien Remy-Martin¹ 

[1] FEMTO-ST Institute, CNRS UMR-6174, Université de Bourgogne Franche-Comté, 15B, Av des Montboucons, 25030 Besançon, France;

关键词: microfluidic sensor;    biosensor;    micro-acoustic sensor;    haemostasis;   

DOI  :  10.3390/proceedings2130940

来源: DOAJ

【 摘 要 】

The contribution focuses on the development of microresonant sensor solution integrated in microfluidic platform for the haemostasis assessment at realistic rheological flow conditions similar to the one in blood vessels. A multi-parameter sensor performs real time analysis of interactions between immobilized collagen and platelets. The detection and characterization of such interactions at controlled flow rates provide information to evaluate the dynamic of each step of primary haemostasis. The microresonant sensor concept was developed and is described in the contribution.

【 授权许可】

Unknown