Non-Invasive Brain Stimulation, a Tool to Revert Maladaptive Plasticity in Neuropathic Pain

Frontiers in Human Neuroscience

Margherita Russo¹  Silvia Marino¹  Rocco Salvatore Calabrò¹  Antonino Naro¹  Angelo Quartarone²  Demetrio Milardi²  Carmen Terranova²  Vincenzo Rizzo²  Alberto Cacciola² 

[1] IRCCS Centro Neurolesi “Bonino Pulejo”;University of Messina;

关键词: plasticity;    neuropathic pain;    tDCS;    TMS;    NIBS;   

DOI  :  10.3389/fnhum.2016.00376

来源: DOAJ

【 摘 要 】

Neuromodulatory effects of non-invasive brain stimulation (NIBS) have been extensively studied in chronic pain.A hypothetic mechanism of action would be to prevent or revert the ongoing maladaptive plasticity within the pain matrix. In this review, the authors discuss the mechanisms underlying the development of an abnormal plasticity in patients with chronic pain and the putative mechanisms of NIBS in modulating synaptic plasticity in neuropathic pain conditions.

【 授权许可】

Unknown