Wonder or evil?: Multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals

Saudi Journal of Biological Sciences

Jarosław Proćków¹  Vaishali Dhaka²  Daljeet Singh Dhanjal²  Dhriti Kapoor³  Abhijit Dey⁴  Samapika Nandy⁴  Manoj Kumar⁵  Uttpal Anand⁶  Eapen P. Koshy⁶  Amritpal Singh⁷  Joginder Singh⁸  Shivika Datta⁹  Sanjay Kumar^1,10  Praveen C. Ramamurthy^1,11  Simranjeet Singh^1,11 

[1] Corresponding authors.;Department of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab 144411, India;Department of Botany, Lovely Professional University, Phagwara, Punjab 144411, India;Department of Life Sciences, Presidency University, Kolkata 700073, West Bengal, India;Department of Life Sciences, School of Natural Science, Central University of Jharkhand, Brambe, Ratu-Lohardaga Road Ranchi, Jharkhand 835205, India;Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, Uttar Pradesh, India;Department of Oral and Maxillofacial Surgery, Indira Gandhi Government Dental College and Hospital, Amphala, Jammu 180012, India;Department of Plant Biology, Institute of Environmental Biology, Wrocław University of Environmental and Life Sciences, Kożuchowska 5b, 51-631 Wrocław, Poland;Department of Zoology, Doaba College, Jalandhar, Punjab 144001, India;Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi 980-8577, Japan;Interdisciplinary Centre for Water Research (ICWaR), Indian Institute of Sciences, Bangalore 560012, Karnataka, India;

关键词: Cannabis sativa;    Tetrahydrocannabinol;    Cannabinoids;    Psychoactive;    Medical marijuana;    Phytochemicals;   

DOI  :  

来源: DOAJ

【 摘 要 】

Cannabis sativa, widely known as ‘Marijuana’ poses a dilemma for being a blend of both good and bad medicinal effects. The historical use of Cannabis for both medicinal and recreational purposes suggests it to be a friendly plant. However, whether the misuse of Cannabis and the cannabinoids derived from it can hamper normal body physiology is a focus of ongoing research. On the one hand, there is enough evidence to suggest that misuse of marijuana can cause deleterious effects on various organs like the lungs, immune system, cardiovascular system, etc. and also influence fertility and cause teratogenic effects. However, on the other hand, marijuana has been found to offer a magical cure for anorexia, chronic pain, muscle spasticity, nausea, and disturbed sleep. Indeed, most recently, the United Nations has given its verdict in favour of Cannabis declaring it as a non-dangerous narcotic. This review provides insights into the various health effects of Cannabis and its specialized metabolites and indicates how wise steps can be taken to promote good use and prevent misuse of the metabolites derived from this plant.

【 授权许可】

Unknown