One-pot synthesis of 1,2,4,5-tetra substituted imidazoles using sulfonic acid functionalized silica (SiO2-Pr-SO3H)

Arabian Journal of Chemistry

Monireh Shakiba Nahad¹  Zeinab Dashtianeh¹  Ghodsi Mohammadi Ziarani¹  Alireza Badiei² 

[1] Department of Chemistry, Alzahra University, P.O. Box 19938939973, Tehran, Iran;School of Chemistry, College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran;

关键词: Sulfonic acid functionalized silica;    SiO2-Pr-SO3H;    Tetrasubstituted imidazoles;    Benzil;    1,2-Diketones;    One-pot reaction;   

DOI  :  10.1016/j.arabjc.2013.11.020

来源: DOAJ

【 摘 要 】

SiO2-Pr-SO3H has been used as an efficient catalyst for an improved and rapid synthesis of 1,2,4,5-tetrasubstituted imidazoles, by four-component, one-pot reaction of 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines in excellent yields under solvent-free conditions.

【 授权许可】

Unknown