INFLUENCE OF S. TYPHI LIPOPOLISACCHARIDE UPON EPITHELIZATION OF SKIN WOUNDS AND EPIDERMAL GROWTH FACTOR SECRETION

Medicinskaâ Immunologiâ

A. V. Kostarnoy¹  P. G. Gancheva¹  L. V. Verkhovskaya¹  B. S. Naroditsky¹  D. Yu. Logunov¹ 

[1] Федеральное Государственное Бюджетное Учреждение «Научно-Исследовательский ИнститутЭпидемиологии и Микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения и социального развития Российской Федерации, Москва;

关键词: bacterial lipopolysaccharide;    wound healing;    epithelization;    epidermal growth factor;   

DOI  :  10.15789/1563-0625-2012-3-223-226

来源: DOAJ

【 摘 要 】

Abstract. Influence of topical application of bacterial lipopolysaccharide (LPS), a Toll-like receptor 4 agonist, upon epithelization process was investigated, using a murine incisional skin wound model. It was shown that topical LPS application accelerates wound epithelization, and this process was associated with increased levels of epidermal growth factor secretion in wounded skin area.

【 授权许可】

Unknown