Droplet Microfluidics for the Production of Microparticles and Nanoparticles

Micromachines

Ye Tian¹  Xueying Wang²  Jianchun Wang²  Liqiu Wang²  Pei Zhao²  Yan Li²  Hanmei Tian²  Jianmei Wang³  Chengyang Wang³  Yeming Gu⁴ 

[1] Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China;Energy Research Institute, Shandong Academy of Sciences, Jinan 250014, China;School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China;Shandong Shengli Co., Ltd., Jinan 250101, China;

关键词: microfluidics;    microparticles;    nanoparticles;    monodisperse;    emulsion;    droplet microfluidics;   

DOI  :  10.3390/mi8010022

来源: DOAJ

【 摘 要 】

Droplet microfluidics technology is recently a highly interesting platform in material fabrication. Droplets can precisely monitor and control entire material fabrication processes and are superior to conventional bulk techniques. Droplet production is controlled by regulating the channel geometry and flow rates of each fluid. The micro-scale size of droplets results in rapid heat and mass-transfer rates. When used as templates, droplets can be used to develop reproducible and scalable microparticles with tailored sizes, shapes and morphologies, which are difficult to obtain using traditional bulk methods. This technology can revolutionize material processing and application platforms. Generally, microparticle preparation methods involve three steps: (1) the formation of micro-droplets using a microfluidics generator; (2) shaping the droplets in micro-channels; and (3) solidifying the droplets to form microparticles. This review discusses the production of microparticles produced by droplet microfluidics according to their morphological categories, which generally determine their physicochemical properties and applications.

【 授权许可】

Unknown