Spectrum of liver lesions hyperintense on hepatobiliary phase: an approach by clinical setting

Insights into Imaging

Ahmed Ba-Ssalamah¹  Domenico Salvatore Gagliano²  Giuseppe Brancatelli²  Federica Vernuccio³  Roberto Cannella³  An Tang⁴ 

[1] Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, General Hospital of Vienna (AKH);Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), University Hospital of Palermo;Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo;Department of Radiology, Centre Hospitalier de l’Université de Montréal (CHUM);

关键词: Liver neoplasms;    Magnetic resonance imaging;    Hepatocellular carcinoma;    Gadoxetate disodium;    Gadobenate dimeglumine;   

DOI  :  10.1186/s13244-020-00928-w

来源: DOAJ

【 摘 要 】

Abstract Hepatobiliary MRI contrast agents are increasingly being used for liver imaging. In clinical practice, most focal liver lesions do not uptake hepatobiliary contrast agents. Less commonly, hepatic lesions may show variable signal characteristics on hepatobiliary phase. This pictorial essay reviews a broad spectrum of benign and malignant focal hepatic observations that may show hyperintensity on hepatobiliary phase in various clinical settings. In non-cirrhotic patients, focal hepatic observations that show hyperintensity in the hepatobiliary phase are usually benign and typically include focal nodular hyperplasia. In patients with primary or secondary vascular disorders, focal nodular hyperplasia-like lesions arise as a local hyperplastic response to vascular alterations and tend to be iso- or hyperintense in the hepatobiliary phase. In oncologic patients, metastases and cholangiocarcinoma are hypointense lesions in the hepatobiliary phase; however, occasionally they may show a diffuse, central and inhomogeneous hepatobiliary paradoxical uptake with peripheral rim hypointensity. Post-chemotherapy focal nodular hyperplasia-like lesions may be tricky, and their typical hyperintense rim in the hepatobiliary phase is very helpful for the differential diagnosis with metastases. In cirrhotic patients, hepatocellular carcinoma may occasionally appear hyperintense on hepatobiliary phase.

【 授权许可】

Unknown