Antibacterial resin monomers based on quaternary ammonium and their benefits in restorative dentistry

Japanese Dental Science Review

Satoshi Imazato¹  Naomi Izutani²  Sai Ma³  Ji-hua Chen³  Fang Li³ 

[1] Department of Biomaterials Science, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan;Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6030, USA;Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, Xi’an 710032, PR China;

关键词: Dental resins;    Monomers;    Quaternary ammonium;    Antibacterial;   

DOI  :  10.1016/j.jdsr.2012.02.003

来源: DOAJ

【 摘 要 】

Antibacterial resin monomers are unique molecules that provide dental resins with “bio-active function”, i.e. the ability to control bacterial infection. They have strong antibacterial activity when unpolymerized and also demonstrate contact inhibitory effects after being polymerized without releasing antibacterial components. Intensive research has been conducted on antibacterial monomers based on quaternary ammonium, such as methacryloyloxydodecylpyridinium bromide (MDPB), focusing on their basic properties and uses in several resinous restoratives. As represented by successful commercialization of an adhesive system incorporating MDPB, quaternary ammonium based antibacterial monomers have the potential for utilization in various restorative materials and regimens, including caries management and pulp care.

【 授权许可】

Unknown