Acceptability of pre-exposure prophylaxis for HIV prevention: facilitators, barriers and impact on sexual risk behaviors among men who have sex with men in Benin

BMC Public Health

Septime Hessou¹  D. Marcel Zannou²  Myrto Mondor³  Souleymane Diabaté³  Ndeye Ndiagna Gning³  Michel Alary³  Georges Batona⁴  Luc Béhanzin⁴  Fernand A. Guédou⁴  Carin Ahouada⁵ 

[1] Centre Interfacultaire de Formation et de Recherche en Environnement pour le Développement Durable (CIFRED/UAC);Centre National Hospitalier et Universitaire Hubert Koutoukou Maga de Cotonou;Centre de recherche du CHU de Québec, Université Laval;Dispensaire des IST, Centre de Santé Cotonou I;Hopital de Zone Allada;

关键词: Acceptability;    PrEP;    HIV;    MSM;    Benin;   

DOI  :  10.1186/s12889-020-09363-4

来源: DOAJ

【 摘 要 】

Abstract Background In Benin, men who have sex with men (MSM) do not always use condoms during anal sex. Pre-exposure prophylaxis (PrEP) using Truvada® (tenofovir disoproxil fumarate / emtricitabine) may be a complementary HIV prevention measure for MSM. This study aimed at identifying the potential facilitators and barriers to the use of PrEP. Methods This was a cross-sectional study conducted in 2018 among male-born MSM aged 18 years or older who reported being HIV-negative or unaware of their HIV status. The participants were recruited by the RDS technique (respondent driven sampling) in six cities of Benin. Logistic regression analyses, adapted to RDS statistical requirements, were performed to identify the factors associated with PrEP acceptability. Results Mean age of the 400 MSM recruited was 26.2 ± 5.0 years. PrEP was known by 50.7% of respondents. The intention to use PrEP was expressed by 90% of MSM. If PrEP effectiveness were 90% or more, 87.8% of the respondents thought they would decrease condom use. In multivariate analysis, the facilitators associated with PrEP acceptability were: not having to pay for PrEP (odds ratio (OR) = 2.39, 95% CI: 1.50–4.46) and its accessibility within MSM networks (OR = 9.82, 95% CI: 3.50–27.52). Only one barrier was significant: the concern that taking PrEP be perceived as marker of adopting HIV risky behaviors (OR = 0.11, 95% CI: 0.04–0.30). Conclusion In Benin, not all MSM know about PrEP. But once well informed, the majority seems willing to use it if made available. The free availability of the drug and its accessibility in the MSM networks are important facilitators. The possibility of decrease in condom use should not be a barrier to the prescription of PrEP if made available.

【 授权许可】

Unknown