A Design Method for FES Bone Health Therapy in SCI

European Journal of Translational Myology

James Shippen¹  William Holderbaum²  Brian Andrews³  Robin Gibbons³  Monica Armengol⁴  William Harwin⁵ 

[1] The Nuffield Department of Surgical Sciences, Oxford;Aspire CREATe group University College London;Department of Bio-Engineering at the University of Reading;Department of Industrial Design, Coventry University;Science and Engineering, Manchester Metropolitan University;

关键词: FES;    Spinal cord injury;    Osteoporosis;    Bone stress, FES rowing;   

DOI  :  10.4081/ejtm.2016.6419

来源: DOAJ

【 摘 要 】

FES assisted activities such as standing, walking, cycling and rowing induce forces within the leg bones and have been proposed to reduce osteoporosis in spinal cord injury (SCI). However, details of the applied mechanical stimulus for osteogenesis is often not reported. Typically, comparisons of bone density results are made after costly and time consuming clinical trials. These studies have produced inconsistent results and are subject to sample size variations. Here we propose a design process that may be used to predict the clinical outcome based on biomechanical simulation and mechano-biology. This method may allow candidate therapies to be optimized and quantitatively compared. To illustrate the approach we have used data obtained from a rower with complete paraplegia using the RowStim (III) system.

【 授权许可】

Unknown