Recent Advances on Inorganic Nanoparticle-Based Cancer Therapeutic Agents

International Journal of Environmental Research and Public Health

Zhiqin Yuan¹  Jing Cheng²  Chengyao Li³  Fenglin Wang³ 

[1] Technology, Technology Center of Hunan Entry-Exit Inspection and Quarantine Bureau, Hunan Academy of Inspection and Quarantine, Changsha 410004, China;;Hunan Key Laboratory of Food Safety Science &School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou 510515, China;

关键词: cancer therapeutic agents;    gold nanoparticles;    magnetic nanoparticles;    upconversion nanoparticles;    mesoporous silica nanoparticles;   

DOI  :  10.3390/ijerph13121182

来源: DOAJ

【 摘 要 】

Inorganic nanoparticles have been widely investigated as therapeutic agents for cancer treatments in biomedical fields due to their unique physical/chemical properties, versatile synthetic strategies, easy surface functionalization and excellent biocompatibility. This review focuses on the discussion of several types of inorganic nanoparticle-based cancer therapeutic agents, including gold nanoparticles, magnetic nanoparticles, upconversion nanoparticles and mesoporous silica nanoparticles. Several cancer therapy techniques are briefly introduced at the beginning. Emphasis is placed on how these inorganic nanoparticles can provide enhanced therapeutic efficacy in cancer treatment through site-specific accumulation, targeted drug delivery and stimulated drug release, with elaborations on several examples to highlight the respective strategies adopted. Finally, a brief summary and future challenges are included.

【 授权许可】

Unknown