Herpesvirus Regulation of Selective Autophagy

Viruses

YoungBong Choi¹  MaiTram Vo¹ 

[1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA;

关键词: herpesviruses;    autophagy;    selective autophagy;    mitophagy;    aggrephagy;    ferritinophagy;   

DOI  :  10.3390/v13050820

来源: DOAJ

【 摘 要 】

Selective autophagy has emerged as a key mechanism of quality and quantity control responsible for the autophagic degradation of specific subcellular organelles and materials. In addition, a specific type of selective autophagy (xenophagy) is also activated as a line of defense against invading intracellular pathogens, such as viruses. However, viruses have evolved strategies to counteract the host’s antiviral defense and even to activate some proviral types of selective autophagy, such as mitophagy, for their successful infection and replication. This review discusses the current knowledge on the regulation of selective autophagy by human herpesviruses.

【 授权许可】

Unknown