Crystal structure of ethyl 2-cyano-3-[(1-ethoxyethylidene)amino]-5-(3-methoxyphenyl)-7-methyl-5H-1,3-thiazolo[3,2-a]pyrimidine-6-carboxylate

Acta Crystallographica Section E: Crystallographic Communications

M. S. Krishnamurthy¹  Noor Shahina Begum¹ 

[1] Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560 001, Karnataka, India;

关键词: crystal structure;    pyrimidine;    thiazolopyrimidine;    thiazolo[3,2-a]pyrimidine;    hydrogen bonding;    π–π stacking interactions;   

DOI  :  10.1107/S2056989015005241

来源: DOAJ

【 摘 要 】

In the title compound, C22H24N4O4S, the central pyrimidine ring adopts a sofa conformation with the ring-junction N atom displaced by 0.2358 (6) Å from the mean plane of the remaining ring atoms. The 3-methoxyphenyl ring, at the chiral C atom opposite the other N atom, is positioned axially and is inclined to the thiazolopyrimidine ring with a dihedral angle of 83.88 (7)°. The thiazole ring is essentially planar (r.m.s. deviation = 0.0034 Å). In the crystal, pairs of weak C—H...O hydrogen bonds link molecules related by twofold rotation axes to form R22(8) rings, which in turn are linked by weak C—H...N interactions, forming ribbons along [-110]. In addition, π–π stacking interactions [centroid—centroid distance = 3.5744 (15) Å] connect the ribbons, forming slabs lying parallel to (001).

【 授权许可】

Unknown