CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3

Journal of Ovarian Research

Lu Zhang¹  Bo Li¹ 

[1] Department of Gynaecology, Yantaishan Hospital;

关键词: SOC;    circSETDB1;    miR-129-3p;    MAP3K3;   

DOI  :  10.1186/s13048-021-00875-0

来源: DOAJ

【 摘 要 】

Highlights 1. CircSETDB1 expression was increased in SOC tissues and cells. 2. CircSETDB1 silencing repressed the malignancy of SOC cells. 3. CircSETDB1 mediated SOC malignant progression by interacting with miR-129-3p. 4. MAP3K3 served as a target gene of miR-129-3p. 5. CircSETDB1 knockdown inhibited tumor formation in vivo.

【 授权许可】

Unknown