Petasis vs. Strecker Amino Acid Synthesis: Convergence, Divergence and Opportunities in Organic Synthesis

Molecules

Wayiza Masamba¹ 

[1] Department of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive, Mthatha 5117, South Africa;

关键词: amino acids;    biomolecules;    multicomponent reactions;    peptides;    Petasis;    Strecker;   

DOI  :  10.3390/molecules26061707

来源: DOAJ

【 摘 要 】

α-Amino acids find widespread applications in various areas of life and physical sciences. Their syntheses are carried out by a multitude of protocols, of which Petasis and Strecker reactions have emerged as the most straightforward and most widely used. Both reactions are three-component reactions using the same starting materials, except the nucleophilic species. The differences and similarities between these two important reactions are highlighted in this review.

【 授权许可】

Unknown