Insulin pump therapy in transient neonatal diabetes mellitus

Annals of Pediatric Endocrinology & Metabolism

Joong Heum Park¹  Eun-Gyong Yoo¹  Jeong Hee Kang¹  Kyu-Hyung Lee¹  Dae-Yeol Lee²  Han-Wook Yoo³  Nam-Hyo Kim⁴ 

[1] Department of Pediatrics, CHA University College of Medicine, Seongnam, Korea.;Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea.;Department of Pediatrics, University of Ulsan College of Medicine, Seoul, Korea.;Sungae Hospital, Seoul, Korea.;

关键词: Diabetes mellitus;    Newborn infant;    Insulin infusion systems;   

DOI  :  10.6065/apem.2013.18.3.148

来源: DOAJ

【 摘 要 】

Neonatal diabetes mellitus (NDM) is a rare disease requiring insulin treatment. Its treatment is primarily focused on maintaining adequate glycemic control and avoiding hypoglycemia. Although insulin pump therapy is frequently administered to adults and children, there is no consensus on the use of insulin pumps in NDM. A 10 day-old female infant was referred to us with intrauterine growth retardation and poor weight gain. Hyperglycemia was noted, and continuous intravenous insulin infusion was initiated. However, the patient's serum glucose levels fluctuated widely, and maintaining the intravenous route became difficult within the following weeks. Continuous subcutaneous insulin infusion with an insulin pump was introduced on the twenty-fifth day of life, and good glycemic control was achieved without any notable adverse effects including hypoglycemia. We suggest that the insulin pump is a safe and effective mode for treating NDM and its early adoption may shorten the length of hospital stays in patients with NDM.

【 授权许可】

Unknown