The effect of hydrostatic pressure on membrane-bound proteins

Brazilian Journal of Medical and Biological Research

S. Scarlata¹ 

[1] SUNY Stony Brook;

关键词: High pressure;    Membrane proteins;    Volume changes;    Protein-membrane associations;    Protein-protein association;    Lateral interactions;   

DOI  :  10.1590/S0100-879X2005000800007

来源: DOAJ

【 摘 要 】

Many cellular proteins are bound to the surfaces of membranes and participate in various cell signaling responses. Interactions between this group of proteins are in part controlled by the membrane surface to which the proteins are bound. This review focuses on the effects of pressure on membrane-associated proteins. Initially, the effect of pressure on membrane surfaces and how pressure may perturb the membrane binding of proteins is discussed. Next, the effect of pressure on the activity and lateral association of proteins is considered. We then discuss how pressure can be used to gain insight into these types of proteins.

【 授权许可】

Unknown