Characterization, Bioactivity and Application of Chitosan-Based Nanoparticles in a Food Emulsion Model

Polymers

Ailén Alemán¹  Pilar Montero¹  M. Carmen Gómez-Guillén¹  M. Elvira López-Caballero¹  Cristian Mauricio Barreto Pinilla²  Carlos Prentice³  Karina Oliveira Lima³ 

[1] Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), 28040 Madrid, Spain;Laboratory of Applied Microbiology and Biochemistry, Institute of Food Science and Technology (ICTA), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS 90650-001, Brazil;Laboratory of Food Technology, School of Chemistry and Food, Federal University of Rio Grande (FURG), Rio Grande, RS 96203-900, Brazil;

关键词: chitosan;    polymeric nanoparticles;    fish protein hydrolysate;    delivery system;    bioactivity;   

DOI  :  10.3390/polym13193331

来源: DOAJ

【 摘 要 】

In this study, chitosan nanoparticles (CNPs) were prepared by the ionic gelation technique with tripolyphosphate (TPP), and the effect of CNP composition and physicochemical characteristics were evaluated. After the synthesis optimization, CNPs were used as carriers for a fish protein hydrolysate (FPH) with bioactive properties (CNPH). The physicochemical characteristics, antioxidant capacity and antimicrobial, antihypertensive and emulsifier properties of unloaded and loaded CNPs in a food system model were studied. CNPH showed a uniform particle distribution, size ~200 nm, high stability (zeta potential around 30 mV), radical scavenging activity and increased antimicrobial activity against Staphylococcus aureus, Shigella sonnei and Aeromonas hydrophila. Additionally, CNPH showed an angiotensin I-converting enzyme (ACE)-inhibitory activity of 63.6% and, when added to a food emulsion model, this system containing CNPs, with or without FHP, exhibited improved food emulsion stability. Thus, CNPs were able to carry the FPH while maintaining their bioactive properties and can be an alternative to the delivery of bioactive peptides with potential as an emulsion stabilizer for food applications.

【 授权许可】

Unknown