F1000Research | |
Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice [v1; ref status: indexed, http://f1000r.es/1jt] | |
Tanya Myers-Morales1  Kate M Bussell1  Sarah EF D'Orazio1  | |
[1] Dept. of Microbiology, Immunology & Molecular Genetics, University of Kentucky, Lexington, KY, USA; | |
关键词: Antimicrobials & Drug Resistance; Bacterial Infections; Immunity to Infections; Immunomodulation; Medical Microbiology; | |
DOI : 10.12688/f1000research.2-177.v1 | |
来源: DOAJ |
【 摘 要 】
The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses. In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota. Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection. Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice. Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.
【 授权许可】
Unknown