Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice [v1; ref status: indexed, http://f1000r.es/1jt]

F1000Research

Tanya Myers-Morales¹  Kate M Bussell¹  Sarah EF D'Orazio¹ 

[1] Dept. of Microbiology, Immunology & Molecular Genetics, University of Kentucky, Lexington, KY, USA;

关键词: Antimicrobials & Drug Resistance;    Bacterial Infections;    Immunity to Infections;    Immunomodulation;    Medical Microbiology;   

DOI  :  10.12688/f1000research.2-177.v1

来源: DOAJ

【 摘 要 】

The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses.  In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota.  Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection.   Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice.  Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.

【 授权许可】

Unknown