Choriocarcinoma brain metastasis in a patient in the third trimester: a case report

Journal of Medical Case Reports

Chunjuan Shen¹  Ling Ai¹  Yunfei Cao¹  Hanbing Wu¹  Dandan Sun¹  Kai Li² 

[1] Department of Obstetrics and Gynecology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing University Affiliated Maternity and Child Hospital;Department of Orthopedics, The Second Hospital of Jiaxing;

关键词: Choriocarcinoma;    Pregnancy;    Metastasis;    Chemotherapy;    Elective caesarean section;   

DOI  :  10.1186/s13256-021-02808-3

来源: DOAJ

【 摘 要 】

Abstract Background Metastatic choriocarcinoma in the third trimester of pregnancy is extremely rare. Case presentation A 25-year-old Chinese woman (gravida 3, para 0) who was 28 weeks pregnant was admitted for sudden convulsion, aconuresis, and unconsciousness. The decision was made to perform an emergency cesarean delivery and craniotomy, hematoma clearance, and decompression. Pathological examination confirmed choriocarcinoma with brain metastasis. The patient underwent chemotherapy with the etoposide, cisplatin (EP) and etoposide, methotrexate and dactinomycin alternating with cyclophosphamide and vincristine (EMACO) regimens. A satisfactory result was achieved. Conclusions When encountering intracranial mass or bilateral pulmonary nodules in a pregnant woman, especially one in the third trimester, metastatic choriocarcinoma should be considered.

【 授权许可】

Unknown