Primary choriocarcinoma of the colon: a case report and review of the literature

World Journal of Surgical Oncology

Xin Peng¹  Jing-Tao Wu¹  Lun Jiang¹ 

[1] Department of Medical Imaging, Su Bei People’s Hospital of JiangSu Province, Medical School of Yangzhou University, No. 98 NanTong West Road, Yangzhou, Jiangsu Province, 225001, China

关键词: Syncytiotrophoblastic differentiation;    Colon;    Choriocarcinoma;    Chemotherapy;    Adenocarcinoma;   

Others  :  826435
DOI  :  10.1186/1477-7819-11-23

 received in 2012-08-08, accepted in 2012-12-24,  发布年份 2013

【 摘 要 】

Choriocarcinoma usually arises in the uterus and gonads. Primary choriocarcinoma (PCC) in an extragenital organ is rare. When it occurs in the gastrointestinal tract, the stomach is the most common site. Only 12 cases of PCC of the colon have been reported in the world literature. Most cases were associated with adenocarcinoma. We report the case of a 36-year-old man with PCC of the colon and review the clinical characteristics of previously documented cases.

【 授权许可】

   
2013 Jiang et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

Figure 3.

【 参考文献 】

• [1]Okubo Y, Fukui I, Sakano Y, Yoshimura K, Maeda H, Yonese J, Yamauchi T, Kawai T, Okumura S, Ishikawa Y: Primary retroperitoneal pure choriocarcinoma. Nihon Hinyokika Gakkai Zasshi 1995, 86:1784-1788.
• [2]Herai Y, Nishi K, Yamamoto H, Mizuguchi M, Kasahara K, Fujimura M: A case of primary choriocarcinoma of the mediastinum in a Japanese woman. Nihon Kokyuki Gakkai Zasshi 2006, 44:384-388.
• [3]Chan HS, Humphreys RP, Hendrick EB, Chuang SH, Fitz CR, Becker LE: Primary intracranial choriocarcinoma: a report of two cases and a review of the literature. Neurosurgery 1984, 15:540-545.
• [4]Harada M, Inoue T, Hamano K: Choriocarcinoma of the sigmoid colon: report of a case. Surg Today 2012, 42:93-96.
• [5]Park CH, Reid JD: Adenocarcinoma of the colon with choriocarcinoma in its metastases. Cancer 1980, 46:570-575.
• [6]Nguyen GK: Adenocarcinoma of the sigmoid colon with focal choriocarcinoma metaplasia: a case report. Dis Colon Rectum 1982, 25:230-234.
• [7]Ordonez NG, Luna MA: Choriocarcinoma of the colon. Am J Gastroenterol 1984, 79:39-42.
• [8]Kubosawa H, Nagao K, Kondo Y, Ishige H, Inaba N: Coexistence of adenocarcinoma and choriocarcinoma in the sigmoid colon. Cancer 1984, 54:866-868.
• [9]Metz KA, Richter HJ, Leder LO: Adenocarcinoma of the colon with syncytiotrophoblastic differentiation: differential diagnosis and implications. Path Res Pract 1985, 179:419-424.
• [10]Lind HM, Haghighi P: Single case reports carcinoembryonic antigen staining in choriocarcinoma. Am J Clin Pathol 1986, 86:538-540.
• [11]Tokisue M, Yasutake K, Oya M, Nishisaki H, Hasegawa H, Sakoda Y, Kizaki T, Sashikata T, Morita R: Coexistence of choriocarcinoma and adenocarcinoma in the rectum: molecular aspects. J Gastroenterol 1996, 31:431-436.
• [12]Kiran RP, Visvanathan R, Simpson CG: Choriocarcinomatous metaplasia of a metachronous adenocarcinoma of the colon. Eur J Surg Oncol 2001, 27:436-437.
• [13]Le DT, Austin RC, Payne SNP, Dworkin MJ, Chappell ME: Choriocarcinoma of the colon: report of a case and review of the literature. Dis Colon Rectum 2003, 46:264-266.
• [14]Verbeek W, Schulten HJ, Sperling M, Tiesmeier J, Stoop H, Dinjens W, Looijenga L, Wörmann B, Füzesi L, Donhuijsen K: Rectal adenocarcinoma with choriocarcinomatous differentiation: clinical and genetic aspects. Hum Pathol 2004, 35:1427-1430.
• [15]Froylich D, Shiloni E, Lavie O, Neumann A, Vlodavsky E, Hazzan D: Colon and lung choriocarcinoma. Isr Med Assoc J 2010, 12:642-644.
• [16]Umemori Y, Hiraki A, Aoe K, Murakami T, Maeda T, Matsuda E, Takeyama H: Primary choriocarcinoma of the lung. Anticancer Res 2004, 24:1905-1910.
• [17]Froylich D, Shiloni E, Lavie O, Neumann A, Vlodavsky E, Hazzan D: Colon and lung choriocarcinoma. IMAJ 2010, 12:642-644.