Bizarre parosteal osteochondromatous proliferation co-occurring with a metatarsal fatigue fracture: a case report

BMC Musculoskeletal Disorders

Xuequn Wu¹  Yanqi Feng¹  Zhaoxiang Fan¹  Ruoyu Yao¹  En Lin Goh² 

[1] Department of Orthopaedics and Traumatology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine;Oxford University Clinical Academic Graduate School, Medical Sciences Division, University of Oxford;

关键词: Bone tumour;    Bizarre parosteal osteochondromatous proliferation;    Nora’s lesion;    Osteochondroma;    Fatigue fracture;   

DOI  :  10.1186/s12891-020-3168-x

来源: DOAJ

【 摘 要 】

Abstract Background Bizarre parosteal osteochondromatous proliferation (BPOP) is a relatively rare benign extraperiosteal osteochondroma-like proliferative lesion that shares similarities with malignant tumours in terms of morphology. The aetiology of BPOP has yet to be determined and there are no previous reports of BPOP associated with fracture. Case presentation A 57-year-old woman presented with a one-month history of pain and swelling in her right foot, which were worsened by activity and improved with rest. Physical examination revealed a hard, non-mobile mass measuring 1.5 cm × 1.5 cm on the dorsal aspect of the third metatarsal of the right foot. There was overlying erythema and tenderness on palpation. Computed tomography (CT) of the right foot demonstrated a fracture of the neck of the third metatarsal, osteolysis at the fracture site and soft tissue swelling. Bone scintigraphy revealed increased tracer uptake suggesting abnormal bone metabolism at the neck of the third metatarsal. Surgical excision of the lesion was performed. Histopathology and immunohistochemistry confirmed the diagnosis of BPOP. Conclusion BPOP is a rare benign lesion that is commonly misdiagnosed. Differential diagnosis is mainly achieved through imaging and histopathological assessment.

【 授权许可】

Unknown