Bizarre parosteal osteochondromatous proliferation: an educational review

Insights into Imaging

Educational Review

Francesca Serpi¹  Simone Mazzoli²  Luca Cannavò²  Alessandro Luzzati²  Domenico Albano²  Luca Maria Sconfienza³  Carmelo Messina³  Salvatore Gitto³  Elisabetta Armiraglio⁴  Andrea Di Bernardo⁴  Antonina Parafioriti⁴ 

[1] Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy;IRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy;IRCCS Istituto Ortopedico Galeazzi, via Cristina Belgioioso 173, 20157, Milan, Italy;Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Milan, Italy;Pathology Department, ASST Pini-CTO, Milan, Italy;

关键词: Bizarre parosteal osteochondromatous proliferation;    Cartilaginous tumor;    Periostitis;    Nora lesion;    Osteochondroma;   

DOI  :  10.1186/s13244-023-01455-0

 received in 2023-02-08, accepted in 2023-05-03,  发布年份 2023

来源: Springer

【 摘 要 】

Bizarre parosteal osteochondromatous proliferation (BPOP) is a surface-based bone lesion belonging to the group of benign chondrogenic tumors. The aim of this review is to familiarize the readers with imaging features and differential diagnosis of BPOP, also addressing pathological presentation and treatment options. The peak of incidence of BPOP is in the third and fourth decades of life, although it can occur at any age. Hands are the most common location of BPOP (55%), followed by feet (15%) and long bones (25%). On imaging, BPOP appears as a well-marginated mass of heterotopic mineralization arising from the periosteal aspect of the bone. Typical features of BPOP are contiguity with the underlying bone and lack of cortico-medullary continuity, although cortical interruption and medullary involvement have been rarely reported. Histologically, BPOP is a benign bone surface lesion characterized by osteocartilaginous proliferation with disorganized admixture of cartilage with bizarre features, bone and spindle cells. Differential diagnosis includes both benign—such as florid reactive periostitis, osteochondroma, subungual exostosis, periosteal chondroma and myositis ossificans—and malignant lesions—such as periosteal chondrosarcoma and surface-based osteosarcoma. Treatment consists of surgical resection. Local recurrences are common and treated with re-excision.Critical relevance statement Bizarre parosteal osteochondromatous proliferation is a benign mineralized mass arising from the periosteal aspect of bone cortex. Multi-modality imaging characteristics, pathology features and differential diagnosis are here highlighted to familiarize the readers with this entity and offer optimal patient care.

【 授权许可】

CC BY   
© The Author(s) 2023

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