Single-step synthesis of AgNPs@rGO composite by e-beam from DC-plasma for wound-healing band-aids

Chemical Engineering Journal Advances

Qing Huang¹  Xinxin Zheng¹  Cao Fang¹  Chao Liu²  Hangbo Xu²  Changsheng Shao² 

[1] Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China;CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Anhui Key Laboratory of Environmental Toxicology and Pollution Control Technology, Institute of Intelligent Machine, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China;

关键词: Silver nanoparticles (AgNPs);    Reduced graphene oxide (rGO);    Non-thermal plasma;    Antibacterial;    Wound healing;    Biomaterials;   

DOI  :  

来源: DOAJ

【 摘 要 】

Currently, there is a huge demand for medical biomaterials aimed to improve antibacterial effect and promote wound healing. In this work, a facile and single-step approach of synthesizing silver nanoparticles (AgNPs) and reduced graphene oxide (rGO) composite material (namely, AgNPs@rGO) using high-voltage direct-current (DC) non-thermal plasma was proposed. Electron-beam (e-beam) from the DC-plasma discharge zone was implanted into the solution of AgNO3 and graphene oxide (GO), leading to the reduction of both GO and silver ions. As a result, AgNPs were formed and distributed homogeneously on the reduced graphene sheets. This composite material exhibits excellent antibacterial performance, being able to kill both Gram-positive bacteria Staphylococcus aureus (S. aureus) and Gram-negative bacteria Escherichia coli (E. coli) effectively. Furthermore, this composite material was utilized to prepare wound-healing band-aids. The in vitro assay on mice confirmed the satisfactory curing effect. The cytotoxicity for bio-compatibility and the mechanism for sterilization were also examined and clarified. As such, this work puts forward a facile and new route of preparing antibacterial biomaterial and demonstrates its promising prospect in wound-healing application.

【 授权许可】

Unknown